A brain-wide map of neural activity during complex behaviour
Overview
Paper Summary
This study used Neuropixels probes to record from over 600,000 neurons in mice performing a decision-making task. They found brain-wide neural correlates of various task elements, including visual stimuli, choices, feedback, and movement, with varying degrees of representation across brain regions. Some regions responded strongly to feedback and movement, while others showed stronger selectivity for visual stimuli or choices.
Explain Like I'm Five
Scientists recorded brain activity in mice doing a task, finding that some brain areas respond to rewards, movement, or choices more strongly than others.
Possible Conflicts of Interest
None identified
Identified Limitations
Rating Explanation
Strong methodology with a large dataset and rigorous analyses, but limited generalizability due to the animal model.
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